The Cardiovascular, Diabetes & Metabolic Disorders (CVDM) Research Center cordially invites you to participate in its 9th annual obesity incubator session. The goal of this session is to bring together BWH clinicians and researchers working in the fields of obesity, diabetes and cardiovascular disease to address this challenging public health crisis by promoting cross-collaborative research efforts and stimulating new ideas for further investigation.

To promote vibrant scientific discussions, the plenary session will feature short talks by selected junior investigators in the field of obesity research, followed by a keynote presentation from Frank A.J.L. Scheer, PhD, Professor of Medicine at Harvard Medical School (HMS) and the Director of the Medical Chronobiology Program (MCP) at Brigham and Women’s Hospital (BWH), Boston. Dr. Scheer’s work focuses on influences of the endogenous circadian system and its disruption—such as with shift work—on cardiovascular, pulmonary, and metabolic regulation and disease states, including hypertension, asthma, obesity and diabetes.

 

Agenda

Poster Session

1:00 – 2:00 PM ET

 

Welcome Remarks

2:00 – 2:05 PM ET

Marie McDonnell, MD
Co-chair of the Cardiovascular, Diabetes and Metabolic Disorders Research Center

 

Featured Short Talks

2:05 – 3:00 PM ET

Deciphering the Kisspeptin-Melanocortin Pathways Underlying the Regulation of Energy Expenditure

Rajae Talbi, PhD

 

High-Fat Diet Causes Rapid Loss of Intestinal Group 3 Innate Lymphoid Cells Through Microbiota-Driven Inflammation

Selma Boulenouar, PhD

 

Discovery and Validation of a Saliva Metabolomic Signature of Insulin Resistance and Diabetes Progression Among Puerto Rican Adults

Danielle Haslam, PhD

 

Keynote Address

3:00 – 4:00 PM ET

Circadian system effects on obesity and metabolism

Frank A.J.L. Scheer, PhD

Professor of Medicine at Harvard Medical School

Director of the Medical Chronobiology Program at Brigham and Women’s Hospital

 

Awards Ceremony

4:00 – 4:15 PM ET

Poster Presenters

 

Hyeon Min Ahn, PhD | BWH

“The association between body mass index and hypothalamus functional connectivity in

response to acute psychosocial stress”

Poster #1, 1st Floor

 

Maria Barrachina, PhD | Boston Children’s Hospital, HMS

“Fatty acid metabolism alteration leads to an impair MKs differentiation and platelet production”

Poster #2, 1st Floor

 

Alexander Blood, MD | BWH

“Reimagining Obesity Care”

Poster #3, 1st Floor

 

Jessica Busler | BWH

“Fractional Amplitude of Low-frequency Fluctuations and Insulin Resistance in Postmenopausal

Women with and without Obesity”

Poster #4, 1st Floor

 

Joanne Cole, PhD | MGH

“Comprehensive genomic analysis of dietary intake elucidates relationships with metabolic

disease”

Poster #5, 1st Floor

 

Yann Cormerais, PhD | Harvard T. H. Chan School of Public Health

“Genetic dissection of the insulin-Akt-mTORC1 pathway for systemic metabolism and insulin

resistance”

Poster #6, 1st Floor

 

Sudeshna Fisch, PhD | BWH

“A basic translational roadmap to understanding DAPA’s mechanism of action in the heart”

Poster #7, 1st Floor

 

Dinah Foer, MD | BWH

“Glucagon-like peptide-1 receptor agonists decrease platelet-mediated airway inflammation”

Poster #8, 1st Floor

 

Renuka Haridas, BVSc, PhD | BWH

“Sleeve gastrectomy alters adipose tissue B cell biology independent of weight”

Poster #9, 1st Floor

 

Frances Hu, MD, MSc | BWH

“Implementing a Bariatric Surgery Digital Intake System for Prospective Collection of Patientreported Outcome Measures”

Poster #10, 1st Floor

 

Nawfal Istfan, MD, PhD | BWH

“Redox Model of Insulin Actions”

Poster #11, 1st Floor

 

Britta Kunkemoeller, PhD | BWH

“The source of dietary fat, not obesity alone, shapes the tumor microenvironment and alters tumor growth”

Poster #1, 2nd Floor

 

Jasmin Lebastchi, MD | Brown, BWH

“Obesity, Diabetes and Hospitalization for COVID-19 Infection”

Poster #2, 2nd Floor

 

Junwei Li | BWH

“Gastrointestinal synthetic epithelial linings for nutritional modulation”

Poster #3, 2nd Floor

 

James Luo, MD | BWH

“Sleeve gastrectomy promotes colitis-associated cancer via a modified microbiome”

Poster #4, 2nd Floor

 

Claire McIntyre, PhD | BWH

“Lipid metabolism fuels IL-17+ γδ T cells in obesity and the tumour microenvironment”

Poster #5, 2nd Floor

 

Christopher Murray, MD, MBA | BWH, MGH

“Assessing the feasibility and acceptability of an ED-initiated Screening, Brief Intervention and Referral to Treatment (SBIRT) approach applied to poor nutrition and lifestyle”

Poster #6, 2nd Floor

 

Kazuma Oyama, MD, PhD | BWH

“Obesity and effects of dapagliflozin on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus in the DECLARE-TIMI 58 trial”

Poster #7, 2nd Floor

 

Adriana Panayi, MD | BWH

“Amniotic Membrane Treatment of an Oxidative Stress Murine Chronic Diabetic Wound Model”

Poster #8, 2nd Floor

 

Karine Suissa, PhD | BWH

“Validation of BMI-related diagnosis codes in claims data”

Poster #9, 2nd Floor

 

Chunlei Tang | BWH

“Evaluating Fairness Criteria in Obesity Subgroups to Assess Risk for Incident Diabetic Complications”

Poster #10, 2nd Floor

 

Wubin Xie, DrPH | BU

“Bariatric Surgery and Weight Loss: Evidence from a US National Sample 2015-2018”

Poster #11, 2nd Floor

 

Hui-Wen Yang, PhD | BWH

“Daily rhythm of fractal cardiac dynamics links to weight loss resistance: interaction with CLOCK3111T/C genetic variant”

Poster #12, 2nd Floor

About the Keynote

Frank A.J.L. Scheer, PhD is Professor of Medicine at Harvard Medical School (HMS) and the Director of the Medical Chronobiology Program (MCP) at Brigham and Women’s Hospital (BWH), Boston. Dr. Scheer’s work focuses on influences of the endogenous circadian system and its disruption—such as with shift work—on cardiovascular, pulmonary, and metabolic regulation and disease states, including hypertension, asthma, obesity and diabetes. Since 2005, Dr. Scheer has been funded continuously as Principal Investigator by the National Institutes of Health (NIH). Dr. Scheer has received numerous scientific awards, including the Young Investigator Award by the American Academy of Sleep Medicine, the Neal Miller Award by the Academy of Behavioral Medicine Research, and the Outstanding Scientific Achievement Award by the Sleep Research Society. Dr. Scheer is an Editorial Board Member of several peer-reviewed journals, is an Associate Editor at the journal SLEEP, and is a Member the Board of Directors of the Sleep Research Society.

Dr. Scheer co-founded and currently directs the MCP, an interdisciplinary research program at BWH to foster the translational research in sleep and circadian biology to understand the basis behind time-variant changes in disease severity, the effects of circadian misalignment (typical in night shift workers), and their interaction with genetics (e.g., the common MTNR1B variant). Understanding the biological basis of these changes across the day and night and their interaction with genetics may help in the development of personalized and time-based behavioral, environmental, and pharmaceutical interventions (e.g. appropriately timed meals, exercise or melatonin to target specific phases of the body clock) to prevent, treat, and/or manage disease.

Have you been confirmed as a poster presenter?

You should reach out to bwhbri@partners.org for more information on how to submit your poster.