9th Annual Obesity Research Incubator

On Friday, May 14, 2021, the Brigham Research Institute’s Cardiovascular, Diabetes, and Metabolic Diseases (CVDM) Research Center hosted the 9th Annual Obesity Research Incubator Session. This was a virtual event featuring a keynote address, several short talks and a poster session. The goal of this event, which attracted almost 70 participants, was to bring together clinicians and researchers working in the fields of obesity, diabetes and cardiovascular disease to address this challenging public health crisis. The annual event, which has grown popular over the years among local researchers, seeks to promote cross-collaborative research efforts and stimulate new ideas for further investigation.  

There were 23 poster presenters, three of whom won prizes of $250. Those who were selected to give short talks during the plenary session received $500. Congratulations to all those who participated and our prestigious winners!

You can find the Program for the event here.

KEYNOTE SPEAKER:

 

Circadian system effects on obesity and metabolism

Frank Scheer, MD

Professor of Medicine, HMS; Director, Medical Chronobiology Program, BWH

Dr. Scheer’s work focuses on influences of the endogenous circadian system and its disruption – such as with shift work – on cardiovascular, pulmonary, and metabolic regulation and disease states, including hypertension, asthma, obesity and diabetes.

 

SHORT TALKS:

 

Deciphering the kisspeptin-melancortin pathways underlying the regulation of energy expenditure

Rajae Talbi, PhD

 

High-Fat Diet Causes Rapid Loss of Intestinal Group 3 Innate Lymphoid Cells Through Microbiota-Drive Inflammation

Selma Boulenouar, PhD

 

Discovery and validation of a saliva metabolomic signature of insulin resistance and diabetes progression among Puerto Rican adults

Danielle Haslam, PhD

 

POSTER WINNERS:

 

Sleeve gastrectomy promotes colitis-associated cancer via a modified microbiome

James Luo, MD

Postdoctoral Fellow, Department of Surgery, BWH

 

Lipid metabolism fuels IL-17+ γδ T cells in obesity and the tumour microenvironment

Claire McIntyre, PhD

Postdoctoral Fellow, Department of Endocrinology, BWH

 

Glucagon-like peptide-1 receptor agonists decrease platelet-mediated airway inflammation

Dinah Foer, MD

Instructor, Department of Allergy and Clinical Immunology, BWH

 

POSTER PRESENTERS:

 

The association between body mass index and hypothalamus functional connectivity in

response to acute psychosocial stress

Hyeon Min Ahn, PhD | BWH

 

Fatty acid metabolism alteration leads to an impair MKs differentiation and platelet production

Maria Barrachina, PhD | Boston Children’s Hospital, HMS

 

 

 Reimagining Obesity Care

Alexander Blood, MD | BWH

 

 

Fractional Amplitude of Low-frequency Fluctuations and Insulin Resistance in Postmenopausal

Women with and without Obesity

Jessica Busler | BWH

 

Comprehensive genomic analysis of dietary intake elucidates relationships with metabolic

Disease

Joanne Cole, PhD | MGH

 

Genetic dissection of the insulin-Akt-mTORC1 pathway for systemic metabolism and insulin

Resistance

Yann Cormerais, PhD | Harvard T. H. Chan School of Public Health

 

A basic translational roadmap to understanding DAPA’s mechanism of action in the heart

Sudeshna Fisch, PhD | BWH

 

Glucagon-like peptide-1 receptor agonists decrease platelet-mediated airway inflammation

Dinah Foer, MD | BWH

 

Sleeve gastrectomy alters adipose tissue B cell biology independent of weight

Renuka Haridas, BVSc, PhD | BWH

 

Implementing a Bariatric Surgery Digital Intake System for Prospective Collection of Patientreported

Outcome Measures

Frances Hu, MD, MSc | BWH

 

Redox Model of Insulin Actions

Nawfal Istfan, MD, PhD | BWH

 

 

The source of dietary fat, not obesity alone, shapes the tumor microenvironment and alters

tumor growth

Britta Kunkemoeller, PhD | BWH

 

Obesity, Diabetes and Hospitalization for COVID-19 Infection

Jasmin Lebastchi, MD | Brown, BWH

 

Gastrointestinal synthetic epithelial linings for nutritional modulation

Junwei Li | BWH

 

Sleeve gastrectomy promotes colitis-associated cancer via a modified microbiome

James Luo, MD | BWH

 

 Lipid metabolism fuels IL-17+ γδ T cells in obesity and the tumour microenvironment

Claire McIntyre, PhD | BWH

 

Assessing the feasibility and acceptability of an ED-initiated Screening, Brief Intervention and

Referral to Treatment (SBIRT) approach applied to poor nutrition and lifestyle

Christopher Murray, MD, MBA | BWH, MGH

 

Obesity and effects of dapagliflozin on cardiovascular and renal outcomes in patients with type

2 diabetes mellitus in the DECLARE-TIMI 58 trial

Kazuma Oyama, MD, PhD | BWH

 

Amniotic Membrane Treatment of an Oxidative Stress Murine Chronic Diabetic Wound Model

Adriana Panayi, MD | BWH

 

Validation of BMI-related diagnosis codes in claims data

Karine Suissa, PhD | BWH

 

Evaluating Fairness Criteria in Obesity Subgroups to Assess Risk for Incident Diabetic

Complications

Chunlei Tang | BWH

 

Bariatric Surgery and Weight Loss: Evidence from a US National Sample 2015-2018

Wubin Xie, DrPH | BU

 

Daily rhythm of fractal cardiac dynamics links to weight loss resistance: interaction with

CLOCK3111T/C genetic variant

Hui-Wen Yang, PhD | BWH



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