AGING AND CARDIOMETABOLIC HEALTH AND DISEASE RESEARCH SYMPOSIUM

DECEMBER 3, 2019 | 2:00 PM – 5:30 PM | MARSHALL A. WOLF CONFERENCE ROOM & HALE CAFE ATRIUM

ABOUT THE EVENT

The Cardiovascular, Diabetes and Metabolic Disorders Center at the Brigham Research Institute will be hosting a research symposium on aging as it relates to cardiometabolic health and disease, which will feature keynote speaker James Mitchell, PhD, Professor of Genetics and Complex Diseases at the Harvard School for Public Health, renowned for his work on dietary restriction and its effects on life span and metabolic fitness. To build bridges between institutions and promote collaborations around this important multidisciplinary topic, the event will be open to all and will feature an interactive program with several short talks and up to 30 posters selected from submitted abstracts. To promote vibrant scientific discussions, researchers from all institutions are invited to submit an abstract for the chance to give a short talk or present a poster.

 

Researchers from all institutions are invited to
submit an abstract to present a poster or give a short talk.

ABSTRACT SUBMISSION DEADLINE - NOVEMBER 11, 2019

REGISTER TO ATTEND
SUBMIT AN ABSTRACT

ABOUT THE KEYNOTE SPEAKER

James Mitchell, PhD

Professor of Genetics & Complex Diseases
Harvard T. H. Chan School of Public Health

James R. Mitchell is Professor of Genetics & Complex Diseases at Harvard T. H. Chan School of Public Health. He received his PhD from the University of California at Berkeley on human telomerase biochemistry, and postdoctoral training at Erasmus Medical Center in Rotterdam, the Netherlands on the genetics of DNA repair and aging. The Mitchell lab studies nutritional, genetic and molecular mechanisms of adaptive stress resistance, with a primary focus on dietary restriction. Dr. Mitchell’s long-term goal is to translate knowledge of anti-aging mechanisms towards improving human health.

Faculty interested in meeting with Dr. Mitchell, please email Trey Toombs 

Fellows and trainees interested in meeting Dr. Mitchell are invited to join him for lunch. The lunch will happen on December 3rd from 12:30 – 1:45 PM. The location will be given out a couple days before the lunch through a confirmation email. 

SCHEDULE

Featuring Keynote Speaker

James Mitchell, PhD
Professor of Genetics and Complex Diseases at the Harvard School for Public Health

2:00 – 4:00 PM

SHORT TALKS BY SELECTED JUNIOR INVESTIGATORS

Marshall A. Wolf Conference Room (Hale Building 3rd Floor)

“Single cell analysis of the mouse aorta reveals and importance of shear stress in driving heterogeneity and the cellular signature of vascular senescence”
Rajat Gupta, MD
Assistant Professor of Medicine
Cardiovascular & Genetics Division
Brigham and Women’s Hospital

 

“LncRNA SNHG12 regulates vascular senescence and atherosclerosis by targeting a DNA-PK-mediated DNA damage response”
Stefan Haemmig, PhD
Research Fellow in Medicine
Cardiovascular Division
Brigham and Women’s Hospital

 

“Age and life expectancy clocks based on machine learning analysis of mouse frailty”
Alice Kane, PhD
Research Fellow in Genetics
Blavatnik Institute, Harvard Medical School

3:00 - 4:00 PM

KEYNOTE ADDRESS

Marshall A. Wolf Conference Room (Hale Building 3rd Floor)

“Benefits of dietary protein restriction on metabolism, resilience and longevity: underlying mechanisms and translational potential”
James R. Mitchell, PhD
Professor of Genetics & Complex Diseases
Harvard T. H. Chan School of Public Health

4:00 - 5:30 PM

POSTER SESSION AND RECEPTION

Hale Cafe Atrium (Hale Building 1st Floor)

Session A:  4:00 – 4:40 PM

1A. Daniel Perez-Cremades, PhD, Brigham and Women’s Hospital – “Role of microRNA-181b in Diabetic Critical
Limb Ischemia”

2A. Ming Tao, MD, Brigham and Women’s Hospital – “Short Term Dietary Methionine Restriction Attenuates Intimal Hyperplasia in a Murine Vein Graft Model”

3A. Elisa Ogawa, PhD, VA Boston Healthcare System – “Metabolic risk and physical performance: the moderating role of cognition among middle to older aged adults”

4A. Jie Hu, MD, PhD, Brigham and Women’s Hospital – “Differences in Metabolomic Profiles between Black and White Postmenopausal Women and the Risk of Coronary Heart Disease in the Women’s Health Initiative”

5A. Weimin Guo, Tufts University – “Dietary fruit and vegetable supplementation suppresses diet-induced atherosclerosis and hepatic steatosis in LDL receptor knockout mice”

6A. Jiahua Li, MD, PhD, Brigham and Women’s Hospital – “Phosphorylated Acetyl-Coa Carboxylase Potentiated Maladaptive Repair After Tubular Injury Leading To Advanced Diabetic Nephropathy”

7A. Michael MacArthur, MS, Harvard T.H. Chan School of Public Health – “Predicting efficacy of lifespan and healthspan extending interventions on an individual level using non-invasive frailty assessment”

8A. Eliezer Bose, PhD, Mass General Hospital – “Diabetic kidney disease and cardiovascular disease linked via gut microbiota and aldosterone”

9A. Ariela Orkaby, MD, MPH, Brigham and Women’s Hospital – “Long-term Aspirin Use is Associated with a Lower Prevalence of Frailty in Men: The Physicians’ Health Study”

 

Session B:  4:50 – 5:10 PM

1B. Peng Li, PhD, Brigham and Women’s Hospital – “Sleep Fragmentation Predicts Incident Heart Failure in Community-Based Older Adults”

2B. Jack Ruske, BA, Brigham and Women’s Hospital – “Patient comprehension necessary for informed consent for vascular procedures is poor and related to frailty”

3B. Lei Gao, MD, Mass General Hospital – “Cardio-autonomic control during exercise is an independent predictor of incident myocardial infarction in 54,681 middle-aged adults during a decade of follow-up from the UK Biobank”

4B. Danielle Haslam, PhD, Brigham and Women’s Hospital – “Plasma metabolomic signatures of the American Heart Association diet score: Findings from the Boston Puerto Rican Health Study”

5B. Laura Holsen, PhD, Brigham and Women’s Hospital – “Memory Network Activation Associated with Insulin Resistance in Postmenopausal Women with Obesity”

6B. Farah Qureshi, ScD, Harvard T.H. Chan School of Public Health – “Aging at the beginning of life: A pilot longitudinal study of telomere length in very preterm infants”

7B. Sarah Mitchell, PhD, Harvard Chan School of Public Health – “Improved healthspan and lifespan with late onset pharmacological or dietary interventions in mice”

8B. Huaner Ni, MD, PhD, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine – “Nicotine modulates cathepsin S synthesis and secretion through autophagy-lysosomal pathway in atherosclerosis”

CALL FOR ABSTRACTS ELIGIBILITY

ABSTRACT SUBMISSION DEADLINE - NOVEMBER 11, 2019

      • Research staff, trainees and faculty with a rank of assistant professor and below are eligible to submit.
      • Abstracts in any area of basic, clinical or translational research related to cardiovascular or metabolic health and aging are welcome.
      • Preference will be given to abstracts describing early stage ideas, novel hypotheses and preliminary or current work.
      • Abstracts that are not selected for short talks will by default be considered for inclusion in the poster session.
      • Successful applicants MUST be available to talk or present a poster on December 3rd.
      • Previously presented research is acceptable for both short talks and posters.
      • Cash prizes will be given to selected speakers and best posters!

POSTER RESOURCE INFORMATION

Are you a poster presenter at Aging and Cardiometabolic Health and Disease Research Symposium? We’ve put together some resources for you to use including logos, templates and resource guides about how to create the best poster for the Poster Session.

 

      • Poster session will take place from 4:00 – 5:30 PM on December 3rd.
      • You can upload your poster in advance by click here. The deadline to submit is December 2nd at 10:00 AM. If you can’t make the deadline you can upload onsite.
      • You can upload your poster onsite from 1:00 – 2:00 PM on December 3rd. We highly recommend that you also bring your file on a flash drive and your laptop on the day for upload.
      • As you begin to create your digital poster presentation, please refer to the attached documents for instructions, templates and recommendations.

 

ePoster BoardsHyperlink Slide Template

ePoster Boards Single Slide Template

ePoster Multiple Slide Template BWH v.1

ePoster Multiple Slides Template BWH  v.2

ePoster Multiple Slide Template BWH  v.3

ePoster Plug & Play Guidelines

ePoster Design Service

FAQ Page

Brigham Health Logo PNG, JPG

DIRECTIONS

Direction to the Marshall A. Wolf Conference Room (Hale Building, 3rd Floor)

From 60 Fenwood Rd:

Enter at 60 Fenwood Rd lobby entrance. STAIRS: Take the lobby staircase to the 2nd floor. Walk past the balcony overlooking the atrium and take the stairs on the left (Stair 2) to the 3rd floor. Once on the 3rd floor, exit the stairwell and take a right. The room is to your right through the double glass door, straight ahead. ELEVATOR: Take S Elevator to 3rd floor. Take a right out of the elevator. The room is past the stairwell, on your right through the double glass doors.

 

 

Direction to Hale Café Atrium (Hale Building, 1st Floor)

From 60 Fenwood Road: Enter at the 60 Fenwood Road entrance.

Elevator:

Take the S elevators to the 1st floor, and the atrium will be on your right. OR at the 60 Fenwood Rd lobby take the stairs up one flight to the 1st floor, and the open atrium will be on your left.

Stairs:

Take the stairs up one flight to the 1st floor, and the open atrium will be on your left.

03dec2:00 pm5:30 pmAging and Cardiometabolic Health and Disease Research Symposium2:00 pm - 5:30 pm Event Type :CVDM Seminar Series

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